Deciphering the Walnut-Pecan Allergy Paradigm Using Component Resolved Diagnostics
نویسندگان
چکیده
منابع مشابه
Component resolved diagnostics for hymenoptera venom allergy
PURPOSE OF REVIEW Component-resolved diagnostics makes use of defined allergen molecules to analyse IgE-mediated sensitizations at a molecular level. Here, we review recent studies on the use of component-resolved diagnostics in the field of Hymenoptera venom allergy (HVA) and discuss its benefits and limitations. RECENT FINDINGS Component resolution in HVA has moved from single molecules to ...
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© Copyright The Korean Academy of Asthma, Allergy and Clinical Immunology • The Korean Academy of Pediatric Allergy and Respiratory Disease http://e-aair.org The gold standard for the diagnosis of IgE-mediated food allergy is an oral food challenge (OFC) that directly verifies the causal relationship between clinical symptoms and offending foods. However, OFC carries a risk of developing fatal ...
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BACKGROUND Not all peanut-sensitized children develop allergic reactions on exposure. OBJECTIVE To establish by oral food challenge the proportion of children with clinical peanut allergy among those considered peanut-sensitized by using skin prick tests and/or IgE measurement, and to investigate whether component-resolved diagnostics using microarray could differentiate peanut allergy from t...
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METHODS. The Auvi-Q and EpiPen were evaluated by each participant in a randomly assigned order. Participantswere given a scenario that involved anaphylaxis and were instructed to simulate the use of each device using trainers that did not have a needle or contain epinephrine. Subjects were expected to perform the device test by relying on the labeling and/or voice instruction or intuition to pe...
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Component-resolved diagnostics (CRD) utilize purified native or recombinant allergens to detect IgE sensitivity to individual allergen molecules and have become of growing importance in clinical investigation of IgE-mediated allergies. This overview updates current developments of CRD, including multiarray test systems. Cross-reactions between allergens of known allergen families (i.e. to Bet v...
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ژورنال
عنوان ژورنال: Journal of Allergy and Clinical Immunology
سال: 2019
ISSN: 0091-6749
DOI: 10.1016/j.jaci.2018.12.785